Dr. Todd M. Preuss


Hecht, E. E., Murphy, L. E., Gutman, D. A., Votaw, J. R., Schuster, D. M., Preuss, T. M., et al. (2013). Differences in neural activation for object-directed grasping in chimpanzees and humans. Journal of Neuroscience, 33(35), 14117–14134. doi:10.1523/JNEUROSCI.2172-13.2013.  PMCID:  PMC3756757 

Chen X, Errangi B, Li L, Glasser MF, Westlye LT, Fjell AM,Walhovd KB, Hu X, Herndon JG, Preuss TM, Rilling JK (2013) Brain aging in humans, chimpanzees (Pan troglodytes) and rhesus macaques (Macaca mulatta): MRI studies of macro- and microstructural changes.  Neurobiol Aging. 2013 Apr 24. [Epub ahead of print]  PMID: 23623601 doi:pii: S0197-4580(13)00147-4. 10.1016/j.neurobiolaging.2013.03.028.  

Li L, Hu X, Preuss TM, Glasser MF, Damen FW, Qiu Y, Rilling J. (2013) Mapping putative hubs in human, chimpanzee and rhesus macaque connectomes via diffusion tractography.  Neuroimage. 2013 Apr 17. doi:pii: S1053-8119(13)00352-2. 10.1016/j.neuroimage.2013.04.024. [Epub ahead of print]  PMID: 23603286 

Glasser MF, Goyal MS Preuss TM, Raichle MC, Van Essen DC (2013) Trends and properties of human cerebral cortex: Correlations with cortical myelin content. Neuroimage. 2013 Apr 6. [Epub ahead of print] PMID: 23567887  doi:pii: S1053-8119(13)00310-8. 10.1016/j.neuroimage.2013.03.060. 

Preuss TM (2012) Human brain evolution: from gene discovery to phenotype discovery. Proc Natl Acad Sci U S A 109 Suppl 1:10709-10716.  PMID: 22723367   Request reprint

Zeng J, Konoka G, Hunt BG, Preuss TM, Geschwind, DH, Yi SJ. Divergent whole genome methylation maps of human and chimpanzee brains reveal epigenetic basis of human regulatory evolution. American Journal of Human Genetics. 91(3):455-65. PMID: 22922032  Request reprint

Konopka, G, Friedrich T, Davis-Turak, J, Winden K, Oldham, MC, Gao F, Chen L, Wang G-Y, Luo R, Preuss TM, Geschwind DH. 2012. Human-specific transcriptional networks in the brain. Neuron 75:601–617.  PMID:  22920253.  Comment by Ponting and OliverRequest reprint

Shulha HP, Crisci JL, Reshetov D, Tushir JS, Cheung I, Bharadwaj R, Chou H-J, Houston IB, Peter CJ, Mitchell AC, Yao WD, Myers RH,Chen JF, Preuss TM, Rogaev EI, Jensen JD, Weng Z, Akbarian S. 2012. Human-specific histone methylation signatures at transcription start sites in prefrontal neurons. PLoS Biology 10(11):e1001427.  PMID:  23185133.

Hecht EE, Gutman DA, Preuss TM, Sanchez MM, Parr LA, Rilling JK (2012) Process versus product in social learning:  Comparative diffusion tensor imaging of neural systems for action execution-observation matching in macaques, chimpanzees, and humans. Cerebral Cortex. PMID: 22539611.

Li L, Rilling JK, Preuss TM, Glasser MF, Damen FW, Hu X (2012) Quantitative assessment of a framework for creating anatomical brain networks via global tractography. NeuroImage:1-53. PMID: 22484406.  PMID:22484406Request reprint

Li L, Rilling JK, Preuss TM, Glasser MF, Hu X (2012) The effects of connection reconstruction method on the interregional connectivity of brain networks via diffusion tractography. Human Brain Mapping 33(8):1894-1913. PMID: 21928316.

Kaas, J.H., and Preuss, T.M. (2012) Human brain evolution. In Fundamental Neuroscience, 4th Edition (eds: L Squire, D Berg, FE Bloom, S du Lac, A Ghosh, NC Spitzer). Academic Press.  pp. 901-918..  Request reprint

Jean S, Preuss TM, Sharma P, Anderson DC, Provenzale JM, Ross SR, Stroud E, Connor-Stroud FC (2012) Cerebrovascular accident (stroke) in captive, group-housed, female chimpanzees. Comparative Medicine 62(4):1-8.  PMID: 23043787  Request reprint

Bryant KL, Suwyn C, Reding KM, Smiley JF, Hackett TA, and Preuss TM. 2012. Evidence for ape and human specializations in geniculostriate projections from VGLUT2 immunohistochemistry. Brain, Behavior and Evolution. Epub 2012 Aug 10.  PMID: 22889767. Request reprint

Preuss, TM. 2012.  Alien brains – a defense of exceptionalism.  In Povinelli, DJ, World Without Weight: Perspectives on an Alien Mind, Oxford, Oxford University Press, pp. 30-31. Request reprint

Povinelli, DJ, Preuss, TM. 2012.  Afterword: A world without apes? In Povinelli, DJ, World Without Weight: Perspectives on an Alien Mind, Oxford, Oxford University Press, pp. 330-332. Request reprint

Rilling J, Glasser M, Jdabdi S, Andersson J, Preuss T (2011) Continuity, divergence, and the evolution of brain language pathways. Front Evol Neurosci 3 (electronic). DOI=10.3389/fnevo.2011.00011.  PMID: 22319495

Preuss TM (2011) The human brain: rewired and running hot. Ann N Y Acad Sci 1225 Suppl 1:E182-191.  PMID: 21599696. Request reprint

Rilling JK, Scholz J, Preuss TM, Glasser MF, Errangi BK, Behrens TE (2011) Differences between chimpanzees and bonobos in neural systems supporting social cognition. Soc Cogn Affect Neurosci. Apr 5. [Epub ahead of print].  PMID: 21467047  Request reprint

Li L, Preuss TM, Rilling JK, Hopkins WD, Glasser MF, Kumar B, Nana R, Zhang X, Hu X (2010) Chimpanzee (Pan troglodytes) precentral corticospinal system asymmetry and handedness: a diffusion magnetic resonance imaging study. PLoS One 5:e12886.  PMID: 20877630.

Bunge, S. and T. M. Preuss (2010). Evolutionary and developmental issues in cognitive neuroscience. Encyclopedia of Behavioral Neuroscience. G. Koob, R. F. Thompson and M. Le Moal. Oxford, Elsevier, pp 512-516.  Request reprint

Preuss, T. M. (2010). Reinventing primate neuroscience for the twenty-first century. Primate Neuroethology. M. L. Platt and A. A. Ghazanfar. Oxford, Oxford University Press: 422-453. Request reprint

Preuss, T. M. (2009). The cognitive neuroscience of human uniqueness. The Cognitive Neurosciences.  Fourth Edition. M. S. Gazzaniga. Cambridge, MA, MIT Press: 49-64.  Request reprint

Parr LA, Hecht E, Barks SK, Preuss TM, Votaw JR. (2009). Face processing in the chimpanzee brain. Curr Biol 19(1): 50-53.

Konopka G, Bomar JM, Winden K, Coppola G, Jonsson ZO, Gao F, Peng S, Preuss TM, Wohlschlegel JA, Geschwind DH. (2009). Human-specific transcriptional regulation of CNS development genes by FOXP2. Nature 462(7270): 213-217.

Balsters J, Cussans E, Diedrichsen J, Phillips KA, Preuss TM, Rilling JK, Ramnani N. (2009). Evolution of the cerebellar cortex: The selective expansion of prefrontal-projecting cerebellar lobules. NeuroImage. Epub 2009/10/28.

Qi, H.-X., T. M. Preuss, et al. (2008). Somatosensory areas of the cerebral cortex: Architectonic characteristics and modular organization. The Senses: A Comprehensive Reference, Vol. 6, Somatosensation. E. P. Gardner and J. H. Kaas. London, Elsevier: 143-170.  Request reprint

Rosen RF, Farberg AS, Gearing M, Dooyema J, Long PM, Anderson DC, Coppola G, Geschwind DH, Pare J, Duong TQ, Hopkins W, Preuss TM, Walker LC  2008. Tauopathy with paired helical filaments in an aged chimpanzee. Journal of Comparative Neurology 508: 259-270.

Rilling, J. K., Glasser, M. F., Preuss, T. M., Ma, X., Zhao, T., Hu, X., and Behrens, T. E. 2008. The evolution of the arcuate fasciculus revealed with comparative DTI. Nature Neuroscience 11:426-428.

Kaas, JH, Preuss, TM  2008. Human brain evolution.  In: Squire LR, Berg D, Bloom FE, du Lac S, Ghosh A, Spizer NC, editors.  Fundamental Neuroscience, Third Edition, pp.  1019-1037.  Amsterdam: Academic Preuss.  Request reprint

Rilling, J.K., Barks, S.K., Parr, L.A., Preuss, T.M., Faber, T.l., Pagnoni, G., Bremner, J.D., and Votaw, J.R.  2007. A comparison of resting state brain activity in humans and chimpanzees. Proceedings of the National Academy of Sciences 104(43):17146-51.

Calarco, J.A., Xing, Y., Caceres, M., Xiao, X., Pan, Q., Lee, C., Preuss, T.M., and Blencowe, B.J.  2007. Alternative splicing differences between humans and chimpanzees affect transcripts from functionally diverse genes. Genes and Development 21(22):2963-75.

Preuss TM. 2007. Primate brain evolution in phylogenetic context. In: Kaas JH, Preuss TM, editors. Evolution of Nervous Sytems Vol 4: The Evolution of Primate Nervous Systems. Oxford: Elsevier, pp. 3-34.   Request reprint

Kaas JH, Preuss TM, editors. 2007. Evolution of Nervous Systems, Vol. 4: The Evolution of Primate Nervous Systems. Oxford: Elsevier.

Preuss TM. 2007. Evolutionary specializations of primate brain systems. In: Ravosa MJ, Dagosto M, editors. Primate Origins: Evolution and Adaptations. New York: Springer, pp. 625-675.  Request reprint

Caceres M, Suwyn C, Maddox M, Thomas JW, Preuss TM. 2007. Increased cortical expression of two synaptogenic thrombospondins in human brain evolution. Cerebral Cortex 17:2312-2321 [Epub 2006 Dec 20].  Get PDF file [1.8 MB].

Stepniewska I, Preuss TM, Kaas JH. 2007. Thalamic connections of the dorsal and ventral premotor areas in New World owl monkeys.  Neuroscience 147(3):727-45.  Get PDF file.

Preuss TM. 2006. Who's afraid of Homo sapiens? Journal of Biomedical Discovery and Collaboration, vol. 1 (available online).  Get PDF file.

Sherwood CC, Raghanti MA, Simpson CD, Bonar CJ, de Sousa AA, Preuss TM, Hof PR. 2006. Scaling of inhibitory interneurons in areas V1 and V2 of anthropoid primates as revealed by calcium-binding protein immunohistochemistry. Brain Behav Evol 69(3):176-195.  Get pdf file.

Stepniewska I, Preuss TM, Kaas JH. 2006. Ipsilateral cortical connections of dorsal and ventral premotor areas in New World owl monkeys. J Comp Neurol 495(6):691-708.  Get PDF file [1.8 MB].

Cola MG, Seltzer B, Preuss TM, Cusick CG. 2005. Neurochemical organization of chimpanzee inferior pulvinar complex. J Comp Neurol 484:299-312.  Get PDF file [1.4 MB].

Povinelli DJ, Prince CG, Preuss TM. 2005. Parent-offspring conflict and the development of social understanding. In: Carruthers P, Laurence S, Stich S, editors. The Innate Mind: Structure and Content: Oxford University Press.

Preuss TM, Caceres M, Oldham MC, Geschwind DH. 2004. Human brain evolution: Insights from microarrays. Nature Reviews Genetics 5:850-860.  Get PDF file [213  KB]

Preuss TM. 2004. What is it like to be a human? In: Gazzaniga MS, editor. The Cognitive Neurosciences III, Third Edition. Cambridge, MA: MIT Press, pp. 5-22.   Request reprint

Marques-Bonet T, Caceres M, Bertranpetit J, Preuss TM, Thomas JW, Navarro A. 2004. Chromosomal rearrangements and the genomic distribution of gene-expression diveregence in humans and chimpanzees. Trends in Genetics 20:524-529.  Get PDF file [199 KB].

Preuss TM. 2004. Specializations of the human visual system: The monkey model meets human reality. In: Kaas JH, Collins CE, editors. The Primate Visual System. Boca Raton, FL: CRC Press. p 231-259.  Request reprint

Caceres M, Lachuer J, Zapala MA, Redmond JC, Kudo L, Geschwind DH, Lockhart DJ, Preuss TM, Barlow C. 2003. Elevated gene expression levels distinguish human from non-human primate brains. PNAS 100:1330-1335.  Get PDF file [666 KB].

Kaas, J.H., and T.M. Preuss, 2003. Human brain evolution. In Fundamental Neuroscience (Second Edition), L.R. Squire, F.E. Bloom, S.K. McConnell, J.L. Roberts,  N.C. Spitzer, and M.J. Zigmond (eds.) San Diego: Academic Press, pp. 1147-1166.   Request reprint

Preuss, T.M., and G.Q. Coleman, 2002.  Human-specific organization of primary visual cortex: Alternating compartments of dense Cat-301 and calbindin immunoreacitivity in layer 4A.  Cereb. Cortex 12: 671-691.  Get PDF file [3.4 MB]  See the cover photo

Hackett, T.A, T.M. Preuss, and J.H. Kaas, 2001. Architectonic identification of the core region in auditory cortex of macaques, chimpanzees, and humans.  J. Comp. Neurol. 441: 197-222.  Get PDF file [2.4 MB] 

Preuss, T.M., 2001. The discovery of cerebral diversity: An unwelcome scientific revolution.  In D. Falk and K. Gibson (eds.): Evolutionary Anatomy of the Primate Cerebral Cortex.  Cambridge: Cambridge University Press, pp. 138-164.   Get PDF file [8.7 MB].

Preuss, TM. (Editor), 2000. The Diversity of Mammalian Cortical Organization.Special symposium edition. Brain, Behavior and Evolution, volume 55.   View table of contents.

Preuss, TM., 2000.  From basic uniformity to diversity in cortical organization.  Brain, Behavior and Evolution 55: 283-286.  Get PDF file [98.1 KB]

Preuss, TM., 2000. Taking the measure of diversity: Comparative alternatives to the model-animal paradigm in cortical neuroscience.  Brain, Behavior and Evolution 55: 287-299. View abstract  / Get PDF file [376.2 KB]

Preuss, T. M., 2000.  What's human about the human brain? In The New Cognitive Neurosciences. Second Edition, M. S. Gazzaniga, ed. Cambridge, MA: MIT Press, pp.  1219-1234.  Get PDF file [14.4 MB]

Preuss, T.M., H.-X. Qi, and J.H. Kaas, 1999. Distinctive compartmental organization of human primary visual cortex. Proceedings of the National Academy of Sciences U.S.A. 96: 11601-11606.  View abstract / Get PDF file [571.4 KB]

Preuss, T. M., and J. H. Kaas, 1999. Human brain evolution. In Fundamental Neuroscience, F. E. Bloom, S. C. Landis, J. L. Robert, L. R. Squire, and M. J. Zigmond, ed. San Diego: Academic Press, pp. 1283-1311.  Get PDF file [17.8 MB].

Qi, H.-X., N. Jain, T.M. Preuss, and J.H. Kaas, 1999. Inverted pyramidal neurons in chimpanzee sensorimotor cortex are revealed by immunostaining with monoclonal antibody SMI-32. Somat. Motor. Res. 16: 49-56.   View abstract / Get PDF file [911.1 KB]

Preuss, T. M., D. Gray, and C. G. Cusick, 1998.  Subdivisions of the motor and somatosensory thalamus of primates revealed with Wisteria floribunda agglutinin histochemistry.  Somat. Motor. Res. 15: 211-219.  View abstract / Get PDF file [2 MB].

Rosa, M., V. A. Casagrande, T. Preuss, and J. H. Kaas, 1997.  Visual field representation in striate and prestriate cortices of a prosimian primate (Galago garnetti).  J. Neurophysiol. 77: 3193-3217.   View abstract / Get PDF file [1.6 MB]

Preuss, T. M., I. Stepniewska, N. Jain, and J. H. Kaas, 1997.  Multiple divisions of macaque precentral motor cortex identified with neurofilament antibody SMI-32.  Brain Res. 767: 148-153.   View abstract / Get PDF file [950 KB]

Preuss, T. M., and J. H. Kaas, 1996.  Cytochrome oxidase "blobs" and other characteristics of primary visual cortex in a lemuroid primate, Cheirogaleus medius.  
Brain Behav. Evol. 47: 103-112.   View abstract  / Get PDF file [11.2 MB]

Preuss, T. M., and J. H. Kaas, 1996.  Parvalbumin-like immunoreactivity of layer V pyramidal cells in the motor and somatosensory cortex of adult primates. Brain Res. 712: 353-357.   View abstract / Request reprint.

Preuss, T. M., I. Stepniewska, and J. H. Kaas, 1996.  Movement representation in the dorsal and ventral premotor areas of owl monkeys: A microstimulation study.  J. Comp. Neurol. 371: 649-676.  View abstract / Get PDF file [48.8 MB]

Preuss, T. M., 1995.  Do rats have prefrontal cortex?  The Rose-Woolsey-Akert program reconsidered. J. Cogn. Neurosci. 7: 1-24.  View abstract & synopsis / Get PDF file [3 MB]

Povinelli, D. J., and T. M. Preuss, 1995.  Theory of mind: Evolutionary history of a cognitive specialization. Trends Neurosci. 18: 418-424.  View abstract / Get PDF file [1.1 MB]

Preuss, T. M., 1995. The argument from animals to humans in cognitive neuroscience. In The Cognitive Neurosciences, M. S. Gazzaniga, ed. Cambridge, MA: MIT Press, pp. 1227-1241.  (Reprinted in Cognitive Neuroscience: A Reader, M.S. Gazzaniga, ed. Oxford: Blackwell Publishers, 2000).  View abstract / Get PDF file [19.5 MB].  

Stepniewska, I., T. M. Preuss, and J. H. Kaas, 1994.  Architectonic subdivisions of the motor thalamus of owl monkeys: Nissl, acetylcholinesterase, and cytochrome oxidase patterns. J. Comp. Neurol.349: 536-557.   View abstract.

Jain, N., T. M. Preuss, and J. H. Kaas, 1994.  Subdivisions of the visual system labeled with the Cat-301 antibody in tree shrews.  Vis. Neurosci. 11: 731-741.  View abstract.

Stepniewska, I., Preuss, T.M., and Kaas, J.H., 1994.  Thalamic connections of the primary motor cortex (M1) of owl monkeys.  J. Comp. Neurol. 349: 558-582.  View abstract.

Preuss, T. M., 1993. The role of the neurosciences in primate evolutionary biology: Historical commentary and prospectus. In Primates and their Relatives in Phylogenetic Perspective, R. D. E. MacPhee, ed. New York: Plenum Press, pp. 333-362.  Get PDF file [6.2 MB]

Kaas, J. H., and T. M. Preuss, 1993. Archontan affinities as reflected in the visual system. In Mammal Phylogeny: Placentals, F. S. Szalay, M. J. Novacek, and M. C. McKenna, ed. New York: Springer Verlag, pp. 115-128.

Stepniewska, I., T. M. Preuss, and J. H. Kaas, 1993.  Architectonics, somatotopic organization, and ipsilateral cortical connections of the primary motor area (M1) of owl monkeys.  J. Comp. Neurol. 330: 238-271.  View abstract.

Preuss, T.M., 1993.  Review of The Meaning of Evolution: The Morphological Construction and Ideological Reconstruction of Darwin's Theory (Robert J. Richards). American Journal of Physical Anthropology, 91: 131-132.

Preuss, T. M., P. D. Beck, and J. H. Kaas, 1993.  Areal, modular, and connectional organization of visual cortex in a prosimian primate, the slow loris (Nycticebus coucang). Brain Behav. Evol. 42: 237-251.  View abstract

Preuss, T. M., and P. S. Goldman-Rakic, 1991.  Myelo- and cytoarchitecture of the granular frontal cortex and surrounding regions in the strepsirhine primate Galago and the anthropoid primate Macaca.J. Comp. Neurol. 310: 429-474.  View abstract / Get PDF file [35.4 MB]

Preuss, T. M., and P. S. Goldman-Rakic, 1991.  Architectonics of the parietal and temporal association cortex in the strepsirhine primate Galago
compared to the anthropoid primate Macaca.J. Comp. Neurol. 310: 475-506.  View abstract.

Preuss, T. M., and P. S. Goldman-Rakic, 1991.  Ipsilateral cortical connections of granular frontal cortex in the strepsirhine primate Galago,with comparative comments on anthropoid primates. J. Comp. Neurol. 310: 507-549.  View abstract.

Preuss, T.M., 1991.  Review of Brain Maturation and Cognitive Development (K.R. Gibson and A.C. Petersen, eds.). Am. J. Phys. Anthropol. 86: 437-438.

Preuss, T. M., and P. S. Goldman-Rakic, 1989.  Connections of the ventral granular frontal cortex of macaques with perisylvian premotor and somatosensory areas: Anatomical evidence for somatic representation in primate frontal association cortex. J. Comp. Neurol. 282: 293-316.  View abstract.

Preuss, T.M., and Goldman-Rakic, P.S., 1987.  Crossed corticothalamic and thalamocortical connections of macaque prefrontal cortex. J. Comp. Neurol. 257: 269-281. View abstract.

Goldman-Rakic, P.S., and Preuss, T.M., 1987.  Wither comparative psychology? (Open peer commentary). Behav. Brain Sci. 10: 666-667.

Preuss, T.M., 1982. The face of Sivapithecus indicus: Description of a new, relatively complete specimen from the Siwaliks of Pakistan. Folia Primatol. 38: 141-157.  View abstract / Get PDF file [7.7 MB]

"Those are my principles.  If you don't like them, I have others."-- Groucho Marx

Links & Images


Yerkes Homepage  | CBN HomepagePreuss Homepage







Webpage maintained by Dr. Todd M. Preuss.
Document last revised 18-September-
(c) Copyright 2013.